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|Glycyrrhizin has also demonstrated antiviral, antimicrobial, anti-inflammatory, hepatoprotective, and blood pressure-increasing effects in vitro and in vivo, as is supported by the finding that intravenous glycyrrhizin (as if it is given orally very little of the original drug makes it into circulation) slows the progression of viral and autoimmune hepatitis. Liquorice has also demonstrated promising activity in one clinical trial, when applied topically, against atopic dermatitis. Additionally, liquorice may be effective in treating hyperlipidaemia (a high amount of fats in the blood). Liquorice has also demonstrated efficacy in treating inflammation-induced skin hyperpigmentation. Liquorice may also be useful in preventing neurodegenerative disorders and dental caries. The antiulcer, laxative, antidiabetic, anti-inflammatory, immunomodulatory, antitumour and expectorant properties of liquorice have been investigated. The compound glycyrrhizin (or glycyrrhizic acid), found in liquorice, has been proposed as being useful for liver protection in tuberculosis therapy, but evidence does not support this use, which may in fact be harmful.
|Liquorice, which grows best in well-drained soils in deep valleys with full sun, is harvested in the autumn two to three years after planting. Countries producing liquorice include Iran, Afghanistan, the People?s Republic of China, Pakistan, Iraq, Azerbaijan, Uzbekistan, Turkmenistan, and Turkey.
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